Mayur Parepally, MD

Mayur Parepally, MD, attended Temple University School of Medicine in Philadelphia, Pennsylvania, earning his medical degree in 2011. He went on to the University of Illinois Chicago, where he completed his Internal Medicine internship and residency in 2014. From there, Dr. Parepally went to the Loyola University Medical Center in Maywood, Illinois, where he completed a Gastroenterology and Hepatology fellowship in 2018. He joined Kelsey-Seybold as a board-certified gastroenterologist in January 2025.

Dr. Parepally became a physician to help other people, following the example of his parents, who both practiced medicine to make a positive impact on their own patients' lives. Dr. Parepally treats a variety of gastrointestinal symptoms and conditions, including acid reflux, abdominal pain and bloating, nausea, vomiting, difficulty swallowing, constipation, and diarrhea. He has particular expertise in the diagnosis and management of inflammatory bowel disease, functional gastrointestinal diseases, and chronic liver disease. Dr. Parepally also helps prevent and diagnose gastrointestinal cancers through screening and other procedures. For Dr. Parepally, the most fulfilling part of practicing medicine is building meaningful bonds with his patients and colleagues.

Dr. Parepally understands that a good doctor-patient relationship is based on open communication and trust, so he strives to create a comfortable environment where patients feel they can confide in him. In order to provide the best care tailored to each individual, he collaborates with his patients, their families, and their other healthcare providers to leverage a multidisciplinary approach for the most effective solutions.

Hobbies and Interests

Dr. Parepally likes to spend time with his family and friends and enjoy all the activities that Houston has to offer. He is also passionate about traveling and experiencing new places and cultures.

Clinical Interests

Dr. Parepally’s clinical interests include new advancements in the management of inflammatory bowel disease and utilizing best practices in preventing colon cancer. He is also committed to patient safety and improving quality outcomes in healthcare.

Awards & Publications

Awards

• Vice Chair of the Section of Gastroenterology, Endeavor Northwest Community Hospital, 2022 — 2024
• Chief Resident in Quality and Patient Safety, Baylor College of Medicine, 2014 — 2015

Publications

Features of Hepatocellular Carcinoma in Hispanics Differ from African Americans and non-Hispanic Whites. World Journal of Gastroenterology. March 2017. Volume 9, Issue 7. Venepalli, NK. Modayil, MV. Berg, SA. Nair, TD. P Parepally, M. Rajaram, P. Gaba, RC. Bui, JT. Huang, Y. Cotler, SJ.

Systematic Review of Transgastric ERCP in Roux-en-y Gastric Bypass Patients. Surgery for Obesity and Related Diseases. February 2017. Banerjee, N. Parepally, M. Byrne, TK. Pullatt, RC. Cote, GA. Elmunzer, BJ.

Incidence and Determinants of Hepatocellular Carcinoma in Autoimmune Hepatitis: A Systematic Review and Meta-Analysis. Clinical Gastroenterology and Hepatology. February 2017. Tansel, A. Katz, LH. El-Serag, HB. Thrift, AP. Parepally, M. Shakhareh, MH. Kanwal, F.

Managing Malignant Biliary Obstruction in Pancreas Cancer: Choosing the Appropriate Strategy. World Journal of Gastroenterology. July 2014. Volume 20, Issue 28. Boulay, BR. Parepally, M.

Prevalence and Risk Factors for Gastroesophageal Reflux Disease in an Impoverished Minority Population. Obesity Resesarch & Clinical Practice. October 2010. Volume 4, Issue 4. Friedenberg, F. Rai, J. Vanar, V. Bongiorno, C. Nelson, D. Parepally, M. Poonia, A. Sharma, A. Gohel, S. Richter, J.

Silencing profilin-1 inhibits endothelial cell proliferation, migration, and cord morphogenesis. Journal of Cell Science. October 2006, Volume 119, Issue 19. Ding, Z. Lambrechts, A. Parepally, M. Roy, P.

Research

Loyola University Medical Center, Maywood, IL January 2016 — June 2018
Division of Hepatology, Division of Gastroenterology and Nutrition

• Investigated the association of bioelectric impedance analysis as a measure of muscle mass in patients undergoing liver transplant evaluation with their clinical outcomes
• Performed a systematic review of transgastric ERCP outcomes in gastric bypass patients

Baylor College of Medicine, Houston, TX July 2014 — June 2015
Division of Gastroenterology and Hepatology, Department of Internal Medicine

• Conducted a retrospective review of cirrhosis-related admissions to determine frequency of readmissions and adverse clinical outcomes
• Created condition-specific order sets for clinical decision support to improve and standardize the care of cirrhotic patients
• Contributed to a systematic review assessing the incidence of hepatocellular carcinoma in patients with autoimmune hepatitis
• Developed a debriefing and peer reflection conference and assessed its ability to provide residents with coping and management strategies after adverse events
• Assessed the effect of a patient safety course on resident physicians’ perspectives

University of Illinois College of Medicine at Chicago, Chicago, IL September 2011 — June 2014
Section of Digestive Diseases and Nutrition

• Published a review article summarizing practices and techniques used in relieving malignant biliary obstruction caused by pancreatic cancer
• Investigated the diagnostic yield of EUS-FNA for cytologic diagnosis of gastric GISTs
• Explored racial differences in clinical presentation and survival of patients with colon cancer
• Initiated a study assessing clinical efficacy of curcumin in conjunction with 5-ASA in IBD

Temple University School of Medicine, Philadelphia, PA May 2008 — July 2010
Section of Gastroenterology

• Conducted a retrospective study of patients who underwent abdominal surgery to examine the correlation between obesity and post-operative complications
• Distributed and analyzed surveys to the North Philadelphia population to understand the prevalence of GERD and its association with risk factors including BMI, age and tobacco use

CRTA Fellowship at the National Cancer Institute, Bethesda, MD July 2006 — July 2007
Postbaccalaureate Fellow in the Laboratory of Cancer Biology and Genetics

• Investigated the mechanism and effects of the cancer therapeutic drug PEP005, used in the treatment of actinic keratosis and basal carcinoma
• Conducted experiments utilizing the mouse skin tumor cell lines PAM212 and 308 to determine the signaling pathway responsible for PEP005-mediated cell death

Bioengineering REU at University of Pittsburgh, Pittsburgh, PA May 2005 — January 2006
Department of Bioengineering

• Explored the biological role of the actin-binding protein Profilin in breast cancer suppression
• Studied local inactivation of Profilin through siRNA and its effects on cell migration

SURP Program at Carnegie Mellon University, Pittsburgh, PA June 2004 — January 2005
Department of Biological Sciences

• Characterized the structural features of Kinesin motor proteins and the role of their secondary microtubule binding domain in processive movement along microtubules
• Designed truncated Kinesin constructs with varying tail lengths containing different sections of the microtubule binding domain