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About Us

​​​​​​Our History


1971 – ​​​2005


In 1971, Kelsey-Seybold Clinic opened its first neighborhood location on Post Oak in the Galleria area. Success resulted in other locations being opened in downtown Houston, Sugar Land, The Woodlands and by Bush Intercontinental Airport. Today, Kelsey-Seybold Clinic has 20 multispecialty clinics in Houston-area neighborhoods.


In 1978, Dr. James C. Hoyle joined the Pediatrics staff. Today, Dr. Hoyle is Medical Director, Clinical Operations.​


Dr. William Seybold retired in 1979. Dr. Seybold was a revered general and thoracic surgeon who served as chief of staff of St. Luke’s Episcopal Hospital from 1968 to 1971, as well as the chief of surgery. He served as the chief of Staff of Kelsey-Seybold Clinic in the early 70s. 
Dr. William D. Seybold joined Kelsey-Seybold in 1951 and played a leading role in the development of Kelsey-Seybold Clinic.

Dr. Seybold met Dr. Kelsey while in medical school at The University of Texas Medical School in Galveston. They became close friends while in training at the Mayo Clinic. Dr. Seybold and Dr. Kelsey, both fifth-generation Texans, were drawn back to Texas to practice in the new Texas Medical Center.

Some people said the concept of a Texas Medical Center would not succeed because it was too far from downtown. But the Texas Medical Center and the Kelsey-Seybold Clinic succeeded well beyond even the founders’ imaginations. Dr. Seybold passed away in July 2004 at the age of 89.


In 1980 and 1981, two more distinguished physicians joined Kelsey-Seybold Clinic: Dr. Spencer R. Berthelsen, an internist, and Dr. John I. Hughes, a gastroenterologist.
Today, Dr. Berthelsen is Chairman of the Board of Managers and Managing Director of Kelsey-Seybold Clinic. Dr. Hughes is Associate Medical Director of Clinical Academic Affairs and Affiliations and former Chief of Gastroenterology.


In 1986, Kelsey-Seybold Clinic sold its 6624 Fannin building to St. Luke’s Hospital and moved into a temporary location in the Doctor’s Center.
Dr. Mavis Kelsey retired, devoting himself to his family, writing more than a dozen books on art, history, genealogy and travel, and engaging in numerous philanthropic activities.


Eight Kelsey-Seybold Fellows were inducted in recognition of their contributions to Kelsey-Seybold: Dr. James Kemper (1994), Dr. Mavis Kelsey, Dr. James Smith and Breaux Castleman (1995), Dr. Stanton Fischer and Vicki Buxton (1996), Dr. Don Owens (1997) and Dr. Earl Beard (1998).


In 1999, Kelsey-Seybold moved into its state-of-the-art Main Campus at 2727 West Holcombe Blvd. The 400,000-square-foot Main Campus building provides primary and specialty care in a single location. It has an outpatient surgery center, an urgent care center, onsite Kelsey Pharmacy, spacious waiting areas, expanded Radiology Department with MRI, a full-service cafeteria and free parking.


The following new Fellows were honored: Dr. Carlos Taboada and Dr. James Boland (2002), Dr. David Mouton (2003), and Dr. James Hoyle and Enoch Freeman (2005).

2005 ​​

Kelsey-Seybold opened the 75,000 square-foot state-of-the-art Fort Bend Medical and Diagnostic Center, offering access to a wide range of primary care and specialty care doctors, expanded pharmacy with drive-thru services, and enhanced diagnostic services such as Magnetic Resonance Imaging (MRI), Computerized Tomography (CT), mammography and X-ray.

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